The rapid development of information technology has offered opportunities for reform of English teaching for English majors. Supported by modern information technology, such as Internet and mobile terminal, the 4A Problem-Based Flipped Classroom teaching has been developed, and an empirical study on this teaching mode has been conducted for one semester and one winter vacation. Through questionnaires and interviews, and after data collection and analyses, we have achieved the result that shows a higher level of students’satisfaction with this mode, and this mode’s effective promotion of students’language ability. Its deficiency comes as greater demands for time, for environment and for teacher’s timely and effective after-class guidance. This paper also offers solutions to improving this mode in end discussions and reflections.