Based on the relevant panel data of Chengdu-Chongqing economic circle from 2011 to 2020， the driving efficiency of the digital economy for regional economic development is demonstrated. Firstly， the comprehensive evaluation index of digital economic development level and regional economic development level of Chengdu-Chongqing economic circle was measured and calculated by entropy evaluation method， and then the relationship between them was empirically studied by using descriptive statistics， ADF test and econometric model construction. It is found that the digital economy of Chengdu-Chongqing economic circle shows an overall fluctuating upward development trend， which provides the new growth drivers and new strengths for the regional economic development； in addition， the higher the degree of government participation， the more positive it is for the regional economic development level. Based on this， three countermeasure suggestions are put forward： to give full play to the radiation effect of the Chengdu-Chongqing dual-core and drive the economic development of non-core cities； to improve the digital economic development level and promote the regional economy to achieve effective qualitative improvement and reasonable quantitative growth； and to improve relevant laws and regulations to guarantee the safety and high-quality development of the regional economy.