The establishment of the learning-oriented party organizations at the grass-roots level in colleges and universities is to meet the need of the times. It is beneficial to strengthen the work effectiveness and educational mission of the grass-roots party organizations. However, there is a phenomenon that the party organizations at the grass-root level are paying less attention to what they should learn. In face of this, the author tries to find out some effective mechanisms to enhance the learning ability of the party organizations. In this paper, emphasis is laid on guiding mechanism, guarantee mechanism, evaluation mechanism and incentive mechanism as well as their influence on the establishment of the learning-oriented party organizations at the grass-roots level in colleges and universities.