It is a major decision in the reform of higher education to encourage the application-oriented transformation for some local undergraduate colleges and universities, which can help to meet the demands of the national strategy, the society and the students. Meanwhile, transformation development is the mission and challenge in new times of higher education in new times, as well as their right path to exist and develop. Xichang College has been conducting researches and practices on the applied talents cultivation as its educational mission for 10 years ever since 2006. Both the running orientation and specialty settings are aimed at serving the local with vocational objectives and practical teaching. In 2015, Xichang College became the only experimental undergraduate college in Sichuan Province pioneering to transform. This paper emphasizes and introduces some related ideas and concrete methods about transformation development based on the 10-year practice, such as“One Promotion”,“Two Orientations”,“Three Changes”, Four Reductions”and“Five Increases”