Big data technology is widely used in the prevention and control of new crown pneumonia epidemic situation. The disclosure of epidemic information improves the effectiveness of epidemic prevention and control, but frequent privacy leaks also expose the problems between epidemic information disclosure and privacy protection. The scope of privacy in the era of big data has been expanded, and individuals should accept restrictions on their privacy for public welfare purposes, but such restrictions should be legal and moderate. In the prevention and control of the new crown pneumonia epidemic situation, the personal privacy protection faces the dilemma such as the failure of the informed consent rule, the conflict between the public interest and the personal privacy interest, the conflict between the public right to know and the personal privacy right. To protect your privacy, you must be strict To make information disclosure of epidemic situation, we must first follow the relevant legal principles to ensure its legality, secondly, guarantee the public's knowledge, consent and supervision power to ensure its transparency, and finally, we must strictly implement the system of privacy tort liability and strictly observe the last legal line of defense for privacy protection.