With the continuous integration of artificial intelligence into ideological and political education， the subject-object relationship in intelligent ideological and political education has undergone new changes， such as human-machine heterogeneous assimilation， human-machine double subject interaction， and human-machine symbiotic harmony. Some human natures grow on the artificial intelligence with its continuous development. In the future， human-machine relationship presents three possibilities： human-machine coordination， human-machine conflicts or human-machine annihilation. In the artificial intelligence environment， the human-machine relationship should be properly harnessed by always giving priority to human values and interests while designing the future and demarcating the possibilities of the artificial intelligence so that human and artificial intelligence can coordinate closely in harmonious mutual-development.