Though lives of people in Yi regions have improved greatly after the poverty alleviation campaign, multiple con- straints such as backward production conditions, delayed infrastructure constructions and lower human capital accumula- tions have come into force and resulted in lack of endogenous development dynamics and poor sustainability of economic development in rural areas. To explore and remedy the shortcomings of the agricultural development in Liangshan Yi re- gions, we first analyzed the current situations and then studied the obstructing factors of the agricultural development in Li- angshan Yi regions based on the transaction cost theory and the economic logic analysis framework of quality agricultural development. Then we proposed effective approaches for Liangshan Yi regions to achieve their quality agricultural develop- ment.