Due to differentiated social interests, imbalanced systems and other factors, the impoverished at the bottom or edge of society often lack both resources and powers, i.e., they are“power-deprived”and“powerless”. Therefore, they need to be empowered to improve their self-profitability. This paper takes New Hope Group as a case to analyze in depth how enterprises should apply the Empowerment Theory to targeted poverty alleviation tasks: for individual empowerment, labor capital of the impoverished could be raised through diversification of education and training opportunities; for joint empowerment, more rights and interests could be won through the establishment of cooperatives to form interests groups; for social empowerment, the social capital of the impoverished can be increased through the innovation of industrial models. In this innovative poverty alleviation model, the impoverished can achieve all-round empowerment and are expected to be permanently alleviated from poverty. Meanwhile, the enterprises could fulfill their social obligations for targeted poverty alleviation and achieve sustainable development.