Based on the perspective of social practice, Marx distinguishes between natural space-time and social historical space-time, transcending the traditional homogenous understanding of natural and social space-time, accomplishing his creative transformation of the space-time view, and forming a new space-time view based on practice. Against a background of globalization, the continual and substantial development of "One Belt, One Road" initiative and China's ever-expanding cooperation with other countries significantly promote the current and future development of related countries, which highlights the theoretical value and practical significance of Marx's social time-space view.